Mol Cell Proteomics
December 2011
The first identification of lysine malonylation substrates and its regulatory enzyme (Abstract)
Nat Chem Biol
January 2011
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells (Abstract)
JAMA
July 2011
Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma (Abstract)
Mol Cell Biol
July 2011
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy (Abstract)
Meth Mol Biol
July 2011
Using ChIP-seq technology to generate high-resolution profiles of histone modifications. (Abstract)
Neurobiol Learn Mem
July 2011
Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity (Abstract)
Neurobiol Aging
July 2011
The epigenetics of Alzheimer's disease--additional considerations (Abstract)
Neurobiol Aging
July 2011
Toward an integrated genetic and epigenetic approach to Alzheimer's disease (Abstract)
Cell Stem Cell
June 2011
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs (Abstract)
Expert Rev Proteomics
June 2011
Advantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions (Abstract)
Carcinogenesis
June 2011
Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells (Abstract)
Anal Biochem
June 2011
Identification of holocarboxylase synthetase chromatin binding sites in human mammary cell lines using the DNA adenine methyltransferase identification technology (Abstract)
Hum Mol Genet
June 2011
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9 (Abstract)
J Biol Chem
May 2011
Cohesin mediates chromatin interactions that regulate mammalian beta-globin expression (Abstract)
Mol Cell
May 2011
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells (Abstract)
Mol Cell Biol
May 2011
REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements (Abstract)
Genome Res
May 2011
Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins (Abstract)
Genome Res
May 2011
Nucleosome fragility reveals novel functional states of chromatin and poises genes for activation (Abstract)
J Nutr Biochem
May 2011
Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18 (Abstract)
PLoS
April 2011
Relationship between body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks (Abstract)
Nature
April 2011
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome (Abstract)
J Am Chem Soc
April 2011
Biophysical Probes Reveal a “Compromise” Nature of the Methyl-lysine Binding Pocket in L3MBTL1 (Abstract)
Proc Natl Acad Sci USA
April 2011
Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin (Abstract)
Nat Methods
May 2011
Chemically defined conditions for human iPSC derivation and culture. (Abstract)
Curr Opin Endocrinol Diabetes Obes
April 2011
Diabetes in pregnancy: glycemia control guidelines and rationale (Abstract)
Epigenetics
April 2011
MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity (Abstract)
J Nutr Biochem
April 2011
Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes (Abstract)
Biochemistry
March 2011
Structure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription (Abstract)
Nature
May 2011
Mapping and analysis of chromatin state dynamics in nine human cell types. (Abstract)
Nat Protoc
March 2011
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling (Abstract)
Cancer Res
March 2011
Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer (Abstract)
Mol Cell Proteomics
March 2011
Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants (Abstract)
Proc Natl Acad Sci USA
March 2011
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine (Abstract)
PLoS
February 2011
Characterization of the contradictory chromatin modifications at the 3’ end of ZNF genes. (Abstract)
Cell
February 2011
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. (Abstract Δ)
Nature
March 2011
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. (Abstract)
Genome Res
February 2011
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin (Abstract)
Epigenetics
February 2011
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation (Abstract)
PLoS
January 2011
Identification of lysine 37 of histone H2B as a novel site of methylation (Abstract)
Nat Rev Genetics
January 2011
Charting histone modifications and the functional organization of mammalian genomes. (Abstract)
PLoS
January 2011
ReadDepth: a parallel R package for detecting copy number alterations from short sequencing reads (Abstract)
Prog Drug Res
January 2011
Dynamics of histone lysine methylation: structures of methyl writers and erasers (Abstract)
Nat Immunol
January 2011
Lysine methylation of the NF-kappaB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-kappaB signaling (Abstract)
Nucleic Acids Res
January 2011
NCBI Epigenomics: a new public resource for exploring epigenomic data sets (Abstract)
Genome Res
December 2010
High-throughput discovery of rare insertions and deletions in large cohorts (Abstract)
Brief Funct Genomics
December 2010
Next generation sequencing based approaches to epigenomics (Abstract)
Chem Biol
November 2010
Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics (Abstract)
J Med Chem
November 2010
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds (Abstract)
J Proteome Res
November 2010
The first global screening of protein substrates bearing protein-bound 3,4-Dihydroxyphenylalanine in Escherichia coli and human mitochondria (Abstract)
Methods
November 2010
DNA methylation profiling using the methylated-CpG island recovery assay (MIRA) (Abstract)
BMC Bioinformatics
November 2010
Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massively parallel DNA sequencing (Abstract)
Proc Natl Acad Sci USA
October 2010
Dimerization of a viral SET protein endows its function (Abstract)
Cancer Biol Ther
October 2010
SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome (Abstract)
Nat Biotechnology
October 2010
Epigenetic modifications in pluripotent and differentiated cells. (Abstract)
Curr Opinion Genetics Dev
October 2010
The roles of PARP1 in gene control and cell differentiation. (Abstract)
Nat Biotechnology
October 2010
Quantitative comparison of genome-wide DNA methylation mapping technologies (Abstract)
Nat Biotechnology
October 2010
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications (Abstract)
J Nutr
September 2010
Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells (Abstract)
Cell Stem Cell
August 2010
Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. (Abstract)
Cell Stem Cell
August 2010
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells (Abstract)
Nat Chem Biol
August 2010
Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3 (Abstract)
Nat Biotechnology
August 2010
Discovery and characterization of chromatin states for systematic annotation of the human genome (Abstract)
Genome Res
September 2010
Bisulfite Patch PCR enables multiplexed sequencing of promoter methylation across cancer samples. (Abstract)
Nat Methods
August 2010
Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. (Abstract)
Nature
July 2010
Evolutionarily Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters. (Abstract)
J Mol Biol
July 2010
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases (Abstract)
Genome Res
July 2010
Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome (Abstract)
J Am Chem Soc
August 2010
Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters (Abstract)
Mol Cell Biol
July 2010
Successful computational prediction of novel imprinted genes from epigenomic features (Abstract)
J Biol Chem
August 2010
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation (Abstract)
Nature
June 2010
Epigenetics as a unifying principle in the aetiology of complex traits and diseases (Abstract)
Genome Res
June 2010
Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping (Abstract)
Nucleic Acids Res
June 2010
A case study in cross-talk: the histone lysine methyltransferases G9a and GLP (Abstract)
J Nutr
June 2010
Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells (Abstract)
Curr Neurol Neurosci
June 2010
Hormonal influences on cognition and risk for Alzheimer's disease (Abstract)
J Cell Physiol
June 2010
Transcriptome study for early hematopoiesis--achievement, challenge and new opportunity (Abstract)
Science
May 2010
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. (Abstract)
Cell Stem Cell
May 2010
Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells (Abstract)
Biochemistry
April 2010
Coordinated chromatin control: structural and functional linkage of DNA and histone methylation (Abstract)
J Nutr Biochem
April 2010
K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts (Abstract)
J Am Chem Soc
March 2010
Bioorthogonal chemical reporters for monitoring protein acetylation (Abstract)
ACS Chem Biol
March 2010
Rational conversion of affinity reagents into label-free sensors for Peptide motifs by designed allostery (Abstract)
J Proteome Res
March 2010
Proteomic dissection of cell type-specific H2AX-interaction protein complex associated with hepatocellular carcinoma (Abstract)
Nat Cell Bio
March 2010
Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae (Abstract)
Arch Biochem Biophys
March 2010
The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation (Abstract)
Nature
February 2010
CHD7 cooperates with PBAF to control multipotent neural crest formation (Abstract)
Nat Methods
February 2010
Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. (Abstract)
Proteomics
March 2010
Unrestrictive Identification of Non-Phosphorylation PTMs in Yeast Kinases by MS and PTMap. (Abstract)
Nat Struct Mol Biol
January 2010
Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases (Abstract)
Nucleic Acids Res
January 2010
A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics (Abstract)
Nucleic Acids Res
January 2010
HRTBLDb: an informative data resource for hormone receptors target binding loci (Abstract)
Harb Symp Quant Biol
January 2010
Nuclear mobility and mitotic chromosome binding: similarities between pioneer transcription factor FoxA and linker histone H1 (Abstract)
Nat Methods
January 2010
CHROMATIN PROFILING by directly sequencing small quantities of immunoprecipitated DNA. (Abstract)
Nature
November 2009
Human DNA methylomes at base resolution show widespread epigenomic differences (Abstract)
J Proteome Res
January 2010
MS/MS/MS reveals false positive identification of histone serine methylation. (Abstract)
J Biol Chem
January 2010
Identification of a functional network of human epigenetic silencing factors. (Abstract)
PLoS
August 2009
Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks (Abstract)
