Stem Cells
September 2011
Radical acceleration of nuclear reprogramming by chromatin remodeling with the transactivation domain of MyoD. (Abstract)
Proc Natl Acad Sci USA
September 6, 2011
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. (Abstract)
PLoS
April 19, 2011
Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma. (Abstract)
Dig Liver Dis
October 2011
MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. (Abstract)
Nucleic Acids Res
December 20, 2011
RNA aptamers that functionally interact with green fluorescent protein and its derivatives. (Abstract)
Oxford Bioinformatics
December 6, 2011
RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing. (Abstract)
Mol Genet Metab
December 2011
Biotinylation is a natural, albeit rare, modification of human histones. (Abstract)
PLoS Genetics
December 2011
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. (Abstract)
Mol Cell Proteomics
December 2011
The first identification of lysine malonylation substrates and its regulatory enzyme (Abstract)
Mol Cell
November 18, 2011
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. (Abstract)
Genes Dev
November 2011
Heat shock reduces stalled RNA polymerase II and nucleosome turnover genome-wide. (Abstract)
Proc Natl Acad Sci USA
November 8, 2011
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer (Abstract)
Cancer Res
December 15, 2011
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. (Abstract)
PLoS
November 2, 2011
Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma. (Abstract)
Comput Methods Programs Biomed
November 2011
Development of an internet based system for modeling biotin metabolism using Bayesian networks. (Abstract)
Genes Dev
November 2011
Pioneer transcription factors: establishing competence for gene expression. (Abstract)
Anal Chem
November 2011
Single DNA molecule patterning for high-throughput epigenetic mapping. (Abstract)
Cell Research
October 2011
Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency. (Abstract)
Hum Mol Genet
September 9, 2011
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. (Abstract)
Cell
September 6, 2011
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification (Abstract)
Meth Mol Biol
August 26, 2011
PARP1 genomics: chromatin immunoprecipitation approach using anti-PARP1 antibody (ChIP and ChIP-seq). (Abstract)
Meth Mol Biol
August 26, 2011
Small-molecule collection and high-throughput colorimetric assay to identify PARP1 inhibitors. (Abstract)
Biochem Biophys Res Commun
August 19, 2011
Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity. (Abstract)
Biochem Cell Biol
November 2011
Cohesin: a critical chromatin organizer in mammalian gene regulation. (Abstract)
Cancer Res
August 11, 2011
Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expression. (Abstract)
Nat Chem Biol
January 2011
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells (Abstract)
JAMA
July 27, 2011
Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma (Abstract)
BJ Cell
August 15, 2011
Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor. (Abstract)
Nucleic Acids Res
October 2011
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. (Abstract)
Nat Protoc
August 2011
Selection of proteins with desired properties from natural proteome libraries using mRNA display. (Abstract)
Mol Cell Biol
July 15, 2011
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy (Abstract)
Proc Natl Acad Sci USA
September 6, 2011
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. (Abstract)
Meth Mol Biol
July 2011
Using ChIP-seq technology to generate high-resolution profiles of histone modifications. (Abstract)
Neurobiol Learn Mem
July 2011
Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity (Abstract)
Neurobiol Aging
July 2011
The epigenetics of Alzheimer's disease--additional considerations (Abstract)
Epigenetics
July 2011
The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events. (Abstract)
Neurobiol Aging
July 2011
Toward an integrated genetic and epigenetic approach to Alzheimer's disease (Abstract)
Nat Genet
August 2011
Increased methylation variation in epigenetic domains across cancer types (Abstract)
BMC Bioinformatics
June 13, 2011
Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta). (Abstract)
Cell Stem Cell
June 3, 2011
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs (Abstract)
Expert Rev Proteomics
June 2011
Advantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions (Abstract)
Carcinogenesis
June 2011
Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells (Abstract)
Anal Biochem
June 2011
Identification of holocarboxylase synthetase chromatin binding sites in human mammary cell lines using the DNA adenine methyltransferase identification technology (Abstract)
Hum Mol Genet
June 2011
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9 (Abstract)
Cell
April 28, 2011
An epigenetic signature for monoallelic olfactory receptor expression (Abstract)
Mol Cell Biol
July 2011
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy. (Abstract)
J Biol Chem
May 20, 2011
Cohesin mediates chromatin interactions that regulate mammalian beta-globin expression (Abstract)
Mol Cell
May 20, 2011
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells (Abstract)
Mol Cell Biol
May 15, 2011
REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements (Abstract)
Genome Res
May 2011
Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins (Abstract)
Genome Res
May 2011
Nucleosome fragility reveals novel functional states of chromatin and poises genes for activation (Abstract)
J Nutr Biochem
May 2011
Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18 (Abstract)
Cell
April 28, 2011
An epigenetic signature for monoallelic olfactory receptor expression. (Abstract)
Neurobiol Learn Mem
July 2011
Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity. (Abstract)
Nucleic Acids Res
August 2011
Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling. (Abstract)
PLoS
April 19, 2011
Relationship between body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks (Abstract)
PLoS
April 2011
Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks. (Abstract)
Nature
April 14, 2011
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome (Abstract)
J Am Chem Soc
April 13, 2011
Biophysical Probes Reveal a “Compromise” Nature of the Methyl-lysine Binding Pocket in L3MBTL1 (Abstract)
Proc Natl Acad Sci USA
April 12, 2011
Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin (Abstract)
Clin Chim Acta
April 11, 2011
A 96-well plate assay for high-throughput analysis of holocarboxylase synthetase activity. (Abstract)
Nat Methods
May 2011
Chemically defined conditions for human iPSC derivation and culture. (Abstract)
Curr Opin Endocrinol Diabetes Obes
April 2011
Diabetes in pregnancy: glycemia control guidelines and rationale (Abstract)
Epigenetics
April 2011
MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity (Abstract)
J Nutr Biochem
April 2011
Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes (Abstract)
Biochemistry
March 29, 2011
Structure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription (Abstract)
Nature
March 24, 2011
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. (Abstract)
Nature
May 5, 2011
Mapping and analysis of chromatin state dynamics in nine human cell types. (Abstract)
Nat Protoc
March 18, 2011
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling (Abstract)
Cancer Res
March 15, 2011
Contribution of inherited mutations in the BRCA2-interacting protein PALB2 to familial breast cancer (Abstract)
Mol Cell Biol
May 2011
REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements. (Abstract)
Nucleic Acids Res
July 2011
Genomic mapping of 5-hydroxymethylcytosine in the human brain. (Abstract)
Mol Cell Proteomics
March 2011
Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants (Abstract)
Proc Natl Acad Sci USA
March 2011
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine (Abstract)
PLoS
February 2011
Characterization of the contradictory chromatin modifications at the 3’ end of ZNF genes. (Abstract)
PLoS
February 2011
Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes. (Abstract)
Cell
February 4, 2011
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. (Abstract Δ)
Nature
March 3, 2011
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. (Abstract)
Genome Res
February 2011
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin (Abstract)
Epigenetics
February 2011
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation (Abstract)
PLoS
January 27, 2011
The role of histone H4 biotinylation in the structure of nucleosomes (Abstract)
PLoS
January 13, 2011
Identification of lysine 37 of histone H2B as a novel site of methylation (Abstract)
Nat Rev Genetics
January 2011
Charting histone modifications and the functional organization of mammalian genomes. (Abstract)
PLoS
January 2011
ReadDepth: a parallel R package for detecting copy number alterations from short sequencing reads (Abstract)
Prog Drug Res
January 2011
Dynamics of histone lysine methylation: structures of methyl writers and erasers (Abstract)
Nat Immunol
January 2011
Lysine methylation of the NF-kappaB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-kappaB signaling (Abstract)
Nucleic Acids Res
January 2011
NCBI Epigenomics: a new public resource for exploring epigenomic data sets (Abstract)
Kidney Int
January 2011
Tracing the footsteps of glomerular insulin signaling in diabetic kidney disease. (Abstract)